Temporary codes (drugs, biologicals, devices)
Q0220 — Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), 300 mg
HCPCS code Q0220 is used on U.S. medical bills for temporary codes (drugs, biologicals, devices): Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), 300 mg.
- Typical setting: Varies
- National avg charge (illustrative): Temporary pricing — confirm with current payer policy.
- Most-disputed reason: Use of Q-code after permanent code was published
What it means
What Q0220 actually means
Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), 300 mg.
The official CMS HCPCS Level II descriptor for this code is shown above. If the description on your bill does not match the service you actually received, that is a reason to ask for the itemized bill and dispute the line.
Common errors with this code
What goes wrong on real bills.
Use these as review prompts, not conclusions. The right next step is to compare the bill, itemized charges, and EOB before paying.
- Quantity or units of service that exceed what the medical record supports.
- Duplicate billing on the same date of service.
- Missing or incorrect modifier (e.g., JW for drug waste, RT/LT for sides).
- Use of Q-code after permanent code was published without supporting documentation.
If you see Q0220 on your bill
Three steps before paying.
1. Get the itemized bill. If your statement only shows a summary, request the CPT-level itemized bill before paying. Generate the request language →
2. Cross-check against the EOB. Compare what your insurer's Explanation of Benefits says you owe versus what the hospital is asking. They disagree more often than people think. Read the bill-vs-EOB guide →
3. Run a free Bill Scan. Upload the bill (and EOB if you have it) and BillBusted will flag the most likely issues with this specific code in your specific state. Run free scan →
Related codes
Other codes in this category.
People who land on Q0220 often also see these adjacent codes on the same bill.
HCPCS
Q0081 — Infusion therapy, using other than chemotherapeutic drugs, per visit
Infusion ther other than che
HCPCS
Q0083 — Chemotherapy administration by other than infusion technique only (e.g., subcutaneous, intramuscular, push), per visit
Chemo by other than infusion
HCPCS
Q0084 — Chemotherapy administration by infusion technique only, per visit
Chemotherapy by infusion
HCPCS
Q0085 — Chemotherapy administration by both infusion technique and other technique(s) (e.g., subcutaneous, intramuscular, push), per visit
Chemo by both infusion and o
HCPCS
Q0091 — Screening papanicolaou smear; obtaining, preparing and conveyance of cervical or vaginal smear to laboratory
Obtaining screen pap smear
Related BillBusted guides
Plain-English reads if you see Q0220 on a bill.
Q0220 FAQ
Plain-English answers.
What is Q0220 used for on a medical bill?
HCPCS code Q0220 is used on medical bills for temporary codes (drugs, biologicals, devices): Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), 300 mg. Billing mistakes can happen, and codes in this category most often get flagged for use of q-code after permanent code was published. If you see Q0220 on your bill, request the itemized statement and compare the units, date of service, and description to your Explanation of Benefits before paying.
How much should Q0220 cost?
How much Q0220 should cost depends on your payer and region. Billing mistakes can happen, and pricing for this HCPCS code is set by Medicare fee schedules for Medicare claims and by negotiated allowed amounts for commercial plans. Check the Medicare fee-schedule lookup tool, your insurer's member portal, or run a free BillBusted scan to compare your charge against typical allowed amounts.
Can I dispute a Q0220 charge on my medical bill?
Yes, you can dispute a Q0220 charge on your medical bill if the units, modifier, date of service, or coverage doesn't match the medical record or your insurance benefits. Request the itemized bill, compare to your EOB, and use BillBusted's Resolution Pack to draft the dispute letter if needed.
Don't pay Q0220 blindly.
The free scan tells you in under 60 seconds whether this charge looks reasonable for your situation.